Protein kinase fun at IPK2019

Brygida, Klaudia, and myself went to the Inhibitors of Protein Kinases 2019 conference organized in Warsaw by the International Union of Biochemistry and Molecular Biology (IUBMB). It had an amazing lineup of speakers, including Tony Hunter, who discovered tyrosine phosphorylation, and Susan Taylor, who first solved the crystal structure of a protein kinase. We attended many inspiring talks and had great conversations with a lot of the attendees. Amazingly, Brygida continues her streak of poster awards! Congratulations! She now has three awards – one for each conference she has attended since joining the lab. Also congrats to her coauthor on that poster, Sylwia, who took some beautiful immunofluorescence pictures that gave the poster a nice “punch”. Brigida’s work is definitely striking a chord with diverse audiences. IUBMB even congratulated her on twitter.

The lab at FEBS 2019

We went to the FEBS 2019 conference in the beautiful city of Kraków. We had a great time. The science was really good and we had tons of fun in the evenings exploring the pubs and restaurants of the historic Kazimierz district. Many thanks to all the people who gave us feedback on our posters and also thanks to all the students and postdocs who presented their excellent posters to me. Congrats to Brygida and Klaudia, whose poster got the “People’s Vote” award! This is already the second time this year that Brygida is getting a poster prize.


We are hiring a postdoc

We are looking for a talented and highly motivated postdoctoral scholar to join our team! The new hire will be able to choose from among some exciting projects that are under development in the lab spanning cell biology (protein transport), molecular biology and biochemistry (Hedgehog signaling), and cancer biology (molecular mechanisms of medulloblastoma and melanoma pathophysiology). To tackle these problems, they will apply state-of-the art methods ranging from bioinformatics, through CRISPR/Cas9 mutagenesis, confocal microscopy, mass spectrometry, to next-generation sequencing. Submit your applications until July 25th. Details below.

PhD students at the Young Scientists Conference

Our valiant team of graduate students participated in the Young Scientists Conference organized by the International Institute for Cell and Molecular Biology. They had a wonderful time talking science at their posters, forging new collaborations, and even winning awards. Brygida got the best poster award for a poster showing off her Master’s degree work. Congrats!

New paper on medulloblastoma transcriptomics

This has been a wonderful collaboration with UCLA (Jim Waschek’s lab) and with the Memorial Children’s Hospital in Warsaw. We found interesting differences between mouse models of Sonic-hedgehog-driven medulloblastoma and actual human cancer.

Thanks guys!

It’s my birthday, and here’s what I saw when I came into my office this morning:

Yes, if you were wondering these are 300 balloons covering the whole of my office. Apparently many of my labbies now have blisters on their fingers from tying up all the balloons. There was also a hedgehog cake, and a wonderful gift.
Thanks guys! You are the best!!!

Lab Christmas party

We had a wonderful Christmas get-together today. Everyone brought home-made Christmas food. Impressive cooking skills all around!

Congrats to Sylwia on her PRELUDIUM grant

Sylwia did it again! After winning the Young Investigator Award from the Department of Biology last year, she has now been awarded a PRELUDIUM grant from the National Science Centre. She placed second out of thirty applications in her study section. The grant will support her efforts at deciphering protein transport to the primary cilium. Congratulations!

Welcome new lab members

Warm welcome to our new lab members. Brygida has started as a PhD student and will work on Gli phosphorylation and the role of cilia in Hedgehog signaling. Ania has recently defended her PhD at the Nencki institute and has come to our lab as a postdoc. She will spearhead work on Hh-dependent ubiquitination and Gli-mediated transcription. Klaudia is a Masters student and will carry out her thesis project on Gli proteins in our lab. Their bios are coming soon to the People page.